Corcoran Lab

@corcoran_lab

Dr. Jenn Corcoran (she/her)
Interested in what viruses have to teach us about cell biology.
FIND ME NOW AT: @corcoranlab.bsky.social

University of Calgary, Canada Joined July 2015

1.1K Following 1.3K Followers 2.1K Posts

Latest posts 5

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Corcoran Lab @corcoran_lab Sep 16

Thrilled to share our most recent paper. Led by the amazing @marielkleer, we show that a viral RNA called kaposin drives nuclear speckle seeding beside the KSHV viral genome, an event which optimizes viral gene expression.

sciencedirect.com/science/articl…

Corcoran Lab @corcoran_lab Sep 17

Nuclear body assembly by a viral repeat RNA promotes Kaposi’s sarcoma-associated herpesvirus gene expression: Molecular Cell cell.com/molecular-cell…

www.cell.com Nuclear body assembly by a viral repeat RNA promotes Kaposi’s sarcoma-associated herpesvirus gene... Kaposin is an abundant viral RNA produced by the virus, Kaposi’s sarcoma-associated herpesvirus (KSHV). Kleer et al. reveal that kaposin drives nuclear speckle formation adjacent to the viral genome,...

Corcoran Lab @corcoran_lab Apr 1

Evolution of a truncated nucleocapsid protein enhances SARS-CoV-2 fitness by suppressing antiviral responses | PLOS Biology journals.plos.org/plosbiology/ar…

journals.plos.org Evolution of a truncated nucleocapsid protein enhances SARS-CoV-2 fitness by suppressing antiviral... SARS-CoV-2 has evolved to optimize its replication fitness in the human host. This study shows that a nucleocapsid gene mutation enhances production of a truncated protein that boosts viral fitness...

Corcoran Lab @corcoran_lab Apr 8, 2025

Don't miss it!

Canadian Society for Virology @CanSocVirol Apr 2, 2025

The CSV virtual trainee event is only 9 days away! Please join to hear talks from three amazing trainees about new virology happening within Canada. The event will take place April 11th at 10 am PT/ 1 pm ET on zoom (link has been circulated to CSV members by email).

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Corcoran Lab @corcoran_lab Mar 17, 2025

Wow huge news and huge congratulations to @DikeakosLab and collaborators on this discovery!

Western University @WesternU Mar 17, 2025

A new #WesternU-led study published in the Lancet Microbe shows the Nef protein could influence the rate at which the latent HIV reservoir shrinks. This discovery opens the door to new strategies to help improve treatments for HIV. @SchulichMedDent
news.westernu.ca/2025/03/potent…
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