Excited to share our latest preprint - a project conceived and driven by Ben Boswell!
Pyridines → anilines via ipso-selective skeletal editing. Predictable molecular remodeling with exciting potential for medicinal chemistry!
tinyurl.com/msyty9aj
chemrxiv.org Ipso-selective pyridine-to-aniline editing through amine-induced fragmentation | ChemRxiv Skeletal editing enables the remodeling of aromatic frameworks, but pyridine-to-aniline conversions can generate multiple positional isomers, complicating analogue synthesis. Here we report an... Pyridines → anilines via ipso-selective skeletal editing. Predictable molecular remodeling with exciting potential for medicinal chemistry!
tinyurl.com/msyty9aj
