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David Okai

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@davidokai

Associate Medical Director, The Maudsley - National Specialist Psychiatry Services | Consultant Neuropsychiatrist. Clinical Director - Maudsley Private
London Joined December 2010
804 Following 1.9K Followers 1K Posts

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David Okai Verified account @davidokai
Pleased with the recent interest in this exciting project below. Our website is now up and running to help clinicians and/or patient volunteers, find out more about the study or enrol. Do please get in touch.

๐Ÿ”ฌ Exciting Opportunity! Weโ€™re recruiting for a MRC funded, groundbreaking โ€˜brain pacemakerโ€™ study to tackle alcohol and opioid addiction through a randomized control trial (RCT). This study leverages Deep Brain Stimulation (DBS), akin to a heart pacemaker, to normalize brain rhythms. Previous trials have shown significant efficacy.

We need:
๐Ÿ”น Alcohol & Opioid use disorder patients
๐Ÿ”น Minimum 5-year addiction history with repeated relapses
๐Ÿ”น Motivated to quit but facing frequent relapses
๐Ÿ”น May be on methadone/buprenorphine with breakthrough use (greater than 1x/week or 5x/month)

Key points:
โœ”๏ธ DBS is FDA/CE approved for Parkinsonโ€™s (since 1997) & OCD (since 2009)
โœ”๏ธ FDA Breakthrough Device approval for addiction (2022)
โœ”๏ธ Safe with over 250,000 devices in use globally

The device targets the nucleus accumbens and ventral internal capsule fibers, similar to successful OCD treatments. Previous RCTs in this area show good results, with some patients achieving prolonged abstinence after years of struggle.

Study design includes physiological mechanism analysis and a clinical RCT, with all participants receiving stimulation in an open-label arm, followed by a crossover trial at six months.

Interested? Join us in pioneering this innovative treatment! ๐ŸŒŸ #AddictionResearch #DBS #ClinicalTrials #BrainPacemaker @valvoon

For more info please see the website: brain-pacer.com

@AlcoholChangeUK @changegrowlive @WeAreWithYou @WeAreWithYou @DDNMagazine @UK_AHA @ActionAddiction @TurningPointUK2 @AlcoholFocus @InstAlcStud
brain-pacer.com Brain-PACER A new treatment study for addictions
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David Okai Verified account @davidokai
What an outstanding achievement for a psychiatrist !!

See his story in a book review I wrote for his book 2022. Explains Optogenetics - hope helpful!
Anthony David @ProfTonyDavid Oct 5
Congratulations - esp @KarlDeisseroth
Only 2nd psychiatrist in history ever to be so awarded.
The 1st Wagner Juaregg (an avowed Nazi) got it for malaria therapy for neurosyphillis - best forgotten
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David Okai Verified account @davidokai
Well done @doctorcordelle !!!!๐Ÿ‘๐Ÿพ๐Ÿ‘๐Ÿพ๐Ÿ‘๐Ÿพ๐ŸŽŠ
Caribbean & African Health Network Verified account @cahn_uk Jul 12, 2025
Congratulations Dr Cordelle Ofori! Winner of the #BlackHealthcareAwards Fenton Award 2025. Your outstanding contributions to healthcare excellence and community service make a lasting impact.
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