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Desi R. Ivanova

@desirivanova

ML+Science. Prev: @UniofOxford, @GoldmanSachs. My opinions are my own. 🇧🇬-🇬🇧 sh/ssh
Oxford, England desirivanova.com Joined December 2014
1.1K Following 959 Followers 1.4K Posts

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Desi R. Ivanova @desirivanova
Incredibly honoured and grateful for this recognition!
We're pleased to reveal the winner of our 3rd #phdprize of the year, this time with @UniofOxford

Learn about our winners, why they were chosen from a host of brilliant submissions and more on our PhD prizes, worth up to £10,000.

eu1.hubs.ly/H09sv3F0
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Desi R. Ivanova @desirivanova
The saddest part is that there's probably more funding and research effort in understanding LLMs than understanding female biology/health.
Bryan Johnson Verified account @bryan_johnson Sep 10
I’ve always been confused by the female experience. I hear what they say, and can conceptually understand what they describe, but I have never been able to internalize the experience myself.

Seeing Kate’s biodata has started to make her more legible to me. It’s kind of how we’re trying to understand AI, a field called mechanistic interpretability where you take a black box and find the underlying circuits that explain the behavior.

Bridging this gap in understanding could unlock far more empathy, cooperation, and alignment.

Remarkably, it seems after 40 days of behavioral consistency (sleep, diet, exercise), her erratic hormonal swings lessened by more than 30% and stabilized.
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Desi R. Ivanova @desirivanova
at this point, I have more faith in Bryan Johnson & his team solving endometriosis than the "traditional" researchers/scientists

One example of how stupidly resources are spent -- pubmed.ncbi.nlm.nih.gov/22985951/ published in a top journal for the field (later retracted, but still WTF)
pubmed.ncbi.nlm.nih.gov Retracted: Attractiveness of women with rectovaginal endometriosis: a case-control study - PubMed Women with rectovaginal endometriosis were judged to be more attractive than those in the two control groups. Moreover, they had a leaner silhouette, larger breasts, and an earlier coitarche.
Bryan Johnson Verified account @bryan_johnson May 23
Examining Kate’s 1%

She has suspected endometriosis. This affects at least 1 in 10 women, likely more.

Here she’s getting an ultrasound.

Historically you needed surgery just to diagnose it (incisions are made in the abdomen). We're doing a non-invasive route.

Typically women live with endometriosis for 7-10 years before being diagnosed. It’s the leading reason women aged 30 to 34 get hysterectomies (permanent surgery to entirely remove the uterus).

This condition is where endometrial-like tissue starts growing outside the uterus, in ovaries, bowel, bladder, even the diaphragm. This tissue inflames, scars, and glues organs together.

Our first step is to find out if @_katetolo has it.

Initial measurements we’re doing:

+ trans vaginal ultrasound
+ pelvic MRI w and w/o contrast
+ hormonal labs

All during the early part of her cycle to get the clearest picture.

During her ultrasound, a slim probe, about the width of two fingers, 10-12 inches long (although only a small portion is inserted) is covered with a protective sheath and lubricant and gently inserted into the vagina (patient has to empty their bladder first). This creates real-time images of the uterus, ovaries, and surrounding pelvic structures. While inserted, the probe is turned 90 degrees to evaluate all the various structures, angles and views. There is no radiation exposure.

The technician is looking for scarring, ovarian cysts, adhesions, and for organs that are fused together with tissue. This ultrasound can confirm endometriosis but it cannot rule it out.

What endo does to the body:

+ 90% report pelvic pain
+ 50% report severe fatigue
+ 26% report infertility. However many sources cite 30 to 50 percent.
+ 50% experience pain during sex.
+ Many have pain with ovulation, bowel movements, and urination
+ Severe bloating called “endo belly” where the abdomen visibly distends

There are a handful of theories about why endometriosis develops but the honest answer is no one is quite sure.

We’ll keep you posted on her results.
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