Koos de Wit

@dewitkoos

MD | PhD | Resident at the Department of Gastroenterology and Hepatology @amsterdamumc

Amsterdam linkedin.com/in/dewitkoos/ Joined July 2010

213 Following 166 Followers 29 Posts

Latest posts 5

Koos de Wit @dewitkoos Feb 6, 2025

Just published in @JAMA_current: the @LiverHope_h2020 trial. Simvastatin and rifaximin for decompensated cirrhosis. @PoseElisa @salvatore_piano @Zac_MD @KGananandan @UschnerFrank @JonelTrebicka @ruben_hernaez @JuanAbraldes jamanetwork.com/journals/jama/… #livertwitter

Koos de Wit @dewitkoos Mar 20, 2024

Extremely proud te be awarded the 🇳🇱 Best Young Basal Hepatologist Award 2024 🏆 @LiverInt @EASLnews @MinnekeC @Saskia_van_Mil @UMCU_CMM @amsterdamumc @spaarnegasthuis onlinelibrary.wiley.com/doi/full/10.11…

Koos de Wit @dewitkoos Feb 19, 2023

💥Proud to be on the cover of @LiverInt 💥

🔬Effects of Rifaximin on human small intestinal organoids:
🧫Stimulation of intracellular nitrogen detoxification
💊Apical excretion into the intestinal lumen

onlinelibrary.wiley.com/toc/14783231/2…
@UMCU_CMM @Saskia_van_Mil @amsterdamumc

onlinelibrary.wiley.com Liver International: Vol 43, No 3 Liver International is a multi-disciplinary hepatology journal promoting all aspects of the field from basic research to applied clinical studies.

Koos de Wit @dewitkoos Jan 2, 2023

@Saskia_van_Mil @UMCU_CMM

Liver International @LiverInt Jan 2, 2023

👋 Take a look at the TOP1 trending article from @LiverInt in social media during the past month:

🔦 #Rifaximin stimulates nitrogen detoxification by PXR-independent mechanisms in human small intestinal organoids

🔓 ow.ly/ymsr50MgQjJ

✍️ @dewitkoos

#livertwitter

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Koos de Wit @dewitkoos Dec 6, 2022

Our paper about direct effects of Rifaximin on the human gastrointestinal epithelium is out @LiverInt
Rifaximin
- stimulates intracellular nitrogen detoxification
- is excreted apically (into the intestinal lumen)
@UMCU_CMM @Saskia_van_Mil
#livertwitter
onlinelibrary.wiley.com/doi/10.1111/li…

onlinelibrary.wiley.com Rifaximin stimulates nitrogen detoxification by PXR‐independent mechanisms in human small intesti... Background and Aims Recurrent hepatic encephalopathy (HE) is characterized by hyperammonaemia in combination with neuropsychiatric abnormalities and is treated with lactulose and rifaximin. Rifaxim...