Alok Sharma

40 year old-HTN, Nephrotic proteinuria & renal dysfunction. Massively enlarged glomeruli with Amyloid deposits staining intensely for Fibrinogen. Notable absence of vascular amyloid deposits. Fibrinogen A alpha chain Amyloidosis.#renalpath #NephTwitter #amyloidosis #PathTwitter

27 mths post Tx, proteinuria & graft dysfunction. PAS+ and silver- mesangium, -ve IF & strong Fibronectin staining(IHC).ACR elsewhere in Bx.EM-vague fibrils. Fibronectin GN often recurs in graft. #FibronectinGN #renalpathology #nephrology #kidneytransplant #rarediagnosis

Proud to be involved in this landmark study! This is a huge step forward in simplifying the diagnostic algorithm for C3 GN's & will pave way for further studies on understanding DDD in greater depth! Absolutely an honour to work with @SethiRenalPath sciencedirect.com/science/articl…

"Blink and miss"... Microfilaria seen in only 4 serial sections of entire biopsy!! Young lady with subnephrotic proteinuria and microhematuria for 3 months, no edema. #PathTwitter #NephTwitter #renalpathology #microfilaria #nephrology #renalbiopsy #pathology

Classical case..young male with sickle cell disease. Creatinine 1.8mg%, 24 hours urine protein 2.4 gm, S.albumin 3.4g%. Marked glomerulomegaly. Sickle cells in LM and EM. Endothelial injury and secondary podocytopathy. #sicklecelldisease #pathology #Nephpearls #renalpathology