The myeloid type I interferon response to myocardial infarction begins in bone marrow and is regulated by Nrf2-activated macrophages immunology.sciencemag.org/content/5/51/e…
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Happy to share new work from our lab! Single cell RNA-Seq of neutrophils monocytes, and macrophages in the peripheral blood of patients and in the bone marrow, blood and heart of mice. biorxiv.org/content/10.110…
www.biorxiv.org Type I interferon responses to ischemic injury begin in the bone marrow of mice and humans and... Sterile tissue injury locally activates innate immune responses via interactions with damage associated molecular patterns (DAMPs). Here, by analyzing ∼120K single cell transcriptomes after myocard...