NOTUS trial just presented at #ATS2024 by @suryapbhatt @uabmedicine and published @NEJM: dupilumab reduced exacerbations by 1/3 in #COPD patients with eosinophils >300. Confirms prior BOREAS trial results.
Matthew Stanbrook
@drstanbrook
Deputy Editor @CMAJ, Associate Professor @uoftmedicine, Respirologist @UHN, Affiliate Scientist @ICESOntario, dad of 2 amazing kids
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Phase 2 COURSE study just presented at #ATS2024 by Dave Singh @OfficialUoM: tezepelumab did not significantly reduce #COPD exacerbations overall, but trends suggested greater benefits in those with higher Th2 inflammation. Suggests phase 3 study should target this population.
ARISE study just presented at #ATS by @CLDaleyMD @NJHealth: liposomal amikacin as add-on to azithromycin + ethambutol was more likely to achieve microbiological clearance of MAC lung disease at 6 months. Also validated QOL-B RD as a PRO measure in MAC.
Huge congrats to Andrea Gershon @uoftmedicine, recipient of the @ATS_BSHSR Lifetime Achievement Award at #ATS2024!
Dmitry Rosenberg @uoftmedicine presenting pilot RCT of cognitive-physical home-based pulmonary rehabilitation right now at #ATS2024. Proud to be collaborating with him on this!
