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Esteban Ballestar

@eballestar

Research Team Leader working on Epigenetics & Immunity | Barcelona
526 Following 984 Followers 805 Posts

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Esteban Ballestar @eballestar
Don't miss this event! Take a look at our outstanding speaker lineup!
📢 Registration is now open for the IJC Symposium 2026!

Join us on 5–6 November in Barcelona to explore the latest advances in the immunology of haematological malignancies and future therapies for blood cancers.

🧬 Free registration
📄 Abstract submissions are now open
🔗 carrerasresearch.org/en/p/immunity-…

Scientific organisers: @eballestar, @BiolaMJavierre & @JTomasNavarro
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Esteban Ballestar @eballestar
Wonderful work, David! The concept that ETC flux—not ATP—licenses cDC1 immunogenicity through /metabolite control of DNA methylation is conceptually beautiful. Congrats to Ignacio, Stefanie and the whole team! Thanks for giving us the chance to learn throught this collaboration!
David Sancho @SanchoLab Apr 18
🤔Do you think that OXPHOS in DCs = tolerance?
🚨In our new @Cell_Metabolism study @CNIC_CARDIO , we show that active #mitochondrial ETC primes cDC1s for immunogenicity, boosting anti-tumor immunity.
Life (and #immunometabolism) is not simple ⚡️(1/9)
OPEN: cell.com/cell-metabolis…
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Esteban Ballestar @eballestar
We’re thrilled to have contributed to this outstanding work led by @JoseL_Sardina & @GemmaValcarcelX! 🧬💡

This study is a milestone in showing that epigenetic editing can causally shape immune identity and inflammatory responses.

@CarrerasIJC
#Epigenetics #CRISPR #Immunology
JL_Sardina_Lab @JoseL_Sardina Jul 17, 2025
1/ Can we control how cells sense external stimuli by modulating their epigenetic states? 🧬🧪

Our latest study shows that targeted DNA methylation editing can shape cell fate & inflammatory responses in immune cells-now out in @ScienceAdvances! 👇

science.org/doi/10.1126/sc…

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