Gregg Fonarow MD

💊 Quadruple GDMT for HFrEF at Cost Plus generic prices:

💵 $0.79/day · $23.83/mo · $290/yr

📉 ↓87% HF 🏨, ↓61% all-cause 🏨

🏥 Avoided hospital costs dwarf the drug cost

✅ Extraordinary value.

🎯 Get every eligible patient on all 4! ❤️

#GDMT @costplusdrugs @mcuban

Viewpoint

Can Payment Reform Transform Heart Failure Care?

“The ASM represents a critical test of whether payment reform can narrow the HF implementation gap.”

@JAMA_current @kejoynt

jamanetwork.com/journals/jama/…

🫀 Only 18.2% of eligible US adults with HFrEF get all 4 GDMT pillars

Close the entire Rx gap:

👥 2.26M patients

⏳ +1.7 to 2.9 life-years each

📈 Up to 6.5 MILLION life-years added

🎯 Go for 100% of eligible patients optimally treated

➡️ Transformative health gains!

“The evidence base for quadruple therapy is settled. Whether policy can serve as the fifth pillar—bridging the gap between what evidence recommends and what patients actually receive—remains to be seen”

jacc.org/doi/10.1016/j.…

National Impact of Optimal Implementation of Guideline-Directed Medical Therapy in Heart Failure With Reduced Ejection Fraction | JACC: Heart Failure jacc.org/doi/10.1016/j.…

@MKIttlesonMD @MKeykhaeiMD @SJGreene_md @ATSandhu @boback @HsuePriscilla @uclaCVfellows @DOM_UCLA