ASHansen Lab
@hansen_lab
We seek to understand the molecular mechanisms that regulate genome organization and gene expression in time and space.
Based in @MITdeptofBE
Based in @MITdeptofBE
18 Following 997 Followers 94 Posts
Latest posts 5
We had a wonderful time celebrating together at our lab’s holiday party, enjoying good company, good food, and a very fun lab trivia. Grateful for a great year and an even better team!
Congrats to @ViraatGoel James Jusuf et al. on new preprint in collab with @Irate_Physicist @blobelgroup @leonidmirny discovering transient microcompartments that connect enhancers and promoters in mitotic chromosomes: biorxiv.org/content/10.110…
www.biorxiv.org Dynamics of microcompartment formation at the mitosis-to-G1 transition As cells exit mitosis and enter G1, mitotic chromosomes decompact and transcription is reestablished. Previously, Hi-C studies showed that essentially all interphase 3D genome features including... (1/n) From @ViraatGoel @Irate_Physicist et al. collab w @blobelgroup @leonidmirny biorxiv.org/content/10.110…
RCMC at the M-to-G1 transition reveals strong microcompartments between CREs (E,P) in mitosis, that weaken upon G1 entry
Sims reveal chromosome compaction as key regulatorView quoted post on X
