JensGeorg

@jensRNA

Biologist with interest in RNA and bioinformatics

Freiburg im Breisgau, Deutschl Joined August 2022

49 Following 26 Followers 11 Posts

Latest posts 4

New breakthrough in @NucleicAcidsRes! Transcriptional Interference (TI) protects Nostoc PCC7120🦠from toxic gene expression. This is the first independent proof that TI can be monitored in vivo via the rifi R-package. doi.org/10.1093/nar/gk…, doi.org/10.1038/s42003…

academic.oup.com Antisense RNA controls the degradation of phycobilisomes in heterocyst-forming cyanobacteria by a... Abstract. Transcriptional interference is rarely documented in bacteria. In cyanobacteria, phycobilisomes are the major light-harvesting antennae, and thei

JensGeorg @jensRNA Jul 9, 2025

Are bacterial sRNA systems inherently more prone to negative regulation?
How relevant is sRNA recycling?
How can we use sRNAs for synthetic biology?
A review with @DSchindler_PDR and Bork Berghoff explores knobs and levers of sRNA-mediated regulation. doi.org/10.1021/acss...

JensGeorg @jensRNA Oct 20, 2023

Check out this preprint about an sRNA that turns E. coli into a fireball. The @ShoshyAltuvia Lab and we could show that the repression of cell division by OxyS is likely a phylogenetically conserved mechanism that is conveyed by a changing target set. 1/2

JensGeorg @jensRNA Jul 21, 2023

Our new paper shows that transcriptional interference by asRNAs is frequent in bacteria. Also RNA stabilty estimates can be significantly improved if the complex transcriptome arcitecture is considered. nature.com/articles/s4200… @CyanolabDE @UniFreiburg @BUnifr @denbiOffice

www.nature.com Improved RNA stability estimation indicates that transcriptional interference is frequent in... Communications Biology - RNA time-series data using rifampicin (an inhibitor of transcription initiation) give insight into transcriptional interference, e.g. by sense/asRNA complex collision, and...