John Hemming

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@johnhemming4mp

Entrepreneur, investor, biohacker and Techie, Jazz pianist, campaigner against injustice.

Birmingham biohackingteam.org Joined January 2010

1.2K Following 11K Followers 11K Posts

Latest posts 5

John Hemming @johnhemming4mp 4d

researchsquare.com/article/rs-116… Which genes' splicing changes with age? A genome-wide analysis of 2.8 million junction tests in GTEx v8

www.researchsquare.com Which genes' splicing changes with age? A genome-wide analysis of 2.8 million junction tests in... Background. Changes in pre-mRNA splicing are a recurrent feature of human aging, but which genes are most and least affected across tissues is not well established. Our earlier analysis of four...

John Hemming @johnhemming4mp 4d

preprints.org/manuscript/202…

Different tissues in the body age in different ways.

www.preprints.org Older and Younger Splicing Across 49 Human Tissues Background. Studies of splicing and age usually count how many events change, and those counts depend heavily on sample size. We asked instead which way each age-linked junction moves — towards use...

John Hemming @johnhemming4mp 5d

John Hemming @johnhemming4mp 5d

rapamycin.news/t/regional-and…

www.rapamycin.news Regional and person-associated variation in age-related intronic RNA across human tissues (preprint... chatGPT(6Max): The paper makes a potentially valuable observational contribution through its regional map of age-associated intronic RNA and its analysis of differences between people. Its findings...

John Hemming @johnhemming4mp 5d

Regional and person-associated variation in age-related intronic RNA across human tissues doi.org/10.5281/zenodo…

zenodo.org Regional and person-associated variation in age-related intronic RNA across human tissues Background. Altered RNA processing is often proposed as a feature of human ageing. Three different changes are easily confused: changes in the abundance of junction-bearing transcripts, changes in...