We just releasd our new docking tool: ProteniX-Dock ! Welcome everyone to try out~
GNU GPL3 so allows commercial use, and has a nice Python interface and CLI😁
Let's dive into it! 🧵View quoted post on X
onlinelibrary.wiley.com The structural landscape of the immunoglobulin fold by large‐scale de novo design De novo designing immunoglobulin-like frameworks that allow for functional loop diversification shows great potential for crafting antibody-like scaffolds with fully customizable structures and... 🚨 We've generated a comprehensive dataset of ~50K high-quality de novo Ig domains, from an in silico screening of ~4M scaffolds, structurally divergent from naturally occurring ones. We uncovered conformational features shaping the structure and function of the Ig fold 🚨View quoted post on X
The structural landscape of the immunoglobulin fold by large-scale de novo design biorxiv.org/cgi/content/sh… #biorxiv_bioinfoView quoted post on X
