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Jue Wang

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@jueseph

Research scientist @googledeepmind. Formerly @UWproteindesign @ginkgo @HMS_SysBio.
London, UK juewang.strikingly.com Joined March 2009
791 Following 3.2K Followers 3K Posts

Latest posts 5

Jue Wang Verified account @jueseph
Tools for Gemini/Antigravity to do chemical reasoning: retrosynthesis, reaction mechanism proposal, etc. Great for enzyme design / engineering and metabolic engineering!
Ruijie (Kelly) Zhang Verified account @kelly_ruijie Nov 3
Have a fun chemistry challenge? Find a talented collaborator in Google Antigravity 🚀

Today we're introducing Cheminformatics Skills
📖 Blog:lnkd.in/eGX-q8jE
🧪 Try it: Install the Science plugin in Antigravity: lnkd.in/etVfMGEb

🧵 1/
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Jue Wang Verified account @jueseph
Introducing AlphaProtein Novo, a pipeline for de novo enzyme design! In collaboration with @francesarnold's group, we developed AP Novo and used it to get SoTA "novel-scaffold" activity on 2 benchmark reactions and create enzymes to synthesize the pharmaceutical motif piperidine and degrade the environmental toxin DEHP.

Work led by @ZvxyWu @ZiqiLi0513 with teammates @alexechu_ @kelly_ruijie @schulluc @jacobjinkelly @rosaliags @davidla @solserpens @j_reisenbauer, @pengliu_group, Josh, Thomas, Amy, Tristan, Harshnira, and others. It was a joy and privilege to work with you all!

Preprints and code:
biorxiv.org/content/10.648…
biorxiv.org/content/10.648…
github.com/google-deepmin…
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Jue Wang Verified account @jueseph
Co-sign. Argon is a game changer for our research on the Protein Design team and I love using it on a day-to-day basis.
Steven Hansen Verified account @Zergylord Oct 1
Honest Argon take: it's not perfect (Opus 5.5 thinking traces are prettier), but it's the first big model we've released that's been this battle tested.

Far from being benchmaxxed, the 200k+ Googlers who rely on it everyday ensured that real utility was prioritized.
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