Karim Beguir

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@kbeguir

Co-Founder & CEO @instadeepai Entrepreneur passionate about developing the ML community. @Google For Startups Mentor, @DeepIndaba Steering Committee Member

London UK instadeep.com Joined November 2011

237 Following 8.6K Followers 1.7K Posts

Latest posts 5

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Karim Beguir @kbeguir Jun 24, 2025

Wow we made the cover of Nature Machine Intelligence @NatMachIntell for the first time! 🥇🚀

ChatNT, our conversational agent for genomics, literally allows you to speak to a dna sequence 🧬

Very proud of the @instadeepai dream team for this historical milestone! ✨

Karim Beguir @kbeguir 5d

I've summarized where things stand at the AI frontier:

- Unreleased models (Anthropic's Models 3 and 4) are now half-way between AI2027's Agents-1 and 2 (graphs fixed for the bug flagged by the AI2027 authors). @DKokotajlo please let me know if I missed something.

- We're right on track with AI2027's prediction of an automated coder (AC) for April 2027, wild. Public models are now massively lagging unreleased models (1 day vs. 1 week of autonomous high-quality work). Fuelled by RSI, the gap is huge and growing.

- This trajectory, if continued, means a world-changing intelligence explosion in 2027, so the public needs to know. I highly recommend reading more on the topic to grasp what's coming.

Karim Beguir @kbeguir 5d

But if the science of AI is done by the models themselves the bitter lesson continues.. 🤷🏻‍♂️

Richard Sutton Verified account @RichardSSutton 6d

Brute force computation is not enough for intelligence. Clever new methods are needed. The science of AI is far from finished. IMHO
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Karim Beguir @kbeguir Nov 2

Hard to believe we are now at this level of capability!

Rikiya Takehi @rikiyatakehi Nov 2

We asked GPT-6 Astra to edit Qwen3.5-0.8B weights to improve math.
It directly changed only 0.016% of weights, fixing 0.8B's reasoning loops & improving math up to 6x and even instruction following 3x, without gradients or training.

We call this Weight-Space Programming: frontier LLMs can now natively read/write neural network weights! 🧵
Blog: rikiyat.github.io/blog/weight-sp…

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Karim Beguir @kbeguir Oct 29

Had a great time discussing Africa’s 🌍new AI prospects with Hassanein Hiridjee, founder and CEO of @axiangroup

Hassanein Hiridjee Verified account @HassanHiridjee Oct 28

AI is moving at a speed few of us anticipated. For Africa, that speed is both the risk and the opportunity.
The full conversation. Available on YouTube, Spotify and all podcast platforms.

@kbeguir

#ChangingAfrica

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