Borde Lab

@lab_borde

We study recombination, chromosomes, meiosis @institut_curie

Joined June 2021

81 Following 564 Followers 286 Posts

Latest posts 5

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Borde Lab @lab_borde Jun 12, 2024

Molecular insights into the activation of Mre11-Rad50 endonuclease activity by Sae2/CtIP: cell.com/molecular-cell…
Check this new paper by our lab, Raphaël Guérois' and @CejkaLab where Alphafold, biochemistry and yeast genetics uncover how pSae2/pCtIP activates Mre11 nuclease!

Borde Lab @lab_borde Nov 24, 2024

We’re off to Bluesky. See you there!

Borde Lab @lab_borde Sep 22, 2024

Synaptonemal complex protects double-Holliday junctions during meiosis biorxiv.org/content/10.110…

www.biorxiv.org Synaptonemal complex protects double-Holliday junctions during meiosis Chromosomal linkages formed through crossover recombination are essential for accurate segregation of homologous chromosomes during meiosis[1][1]. DNA events of recombination are spatially and...

Borde Lab @lab_borde Aug 19, 2024

The MRE11-RAD50-NBS1 complex both starts and extends DNA end resection in mouse meiosis biorxiv.org/content/10.110…

www.biorxiv.org The MRE11-RAD50-NBS1 complex both starts and extends DNA end resection in mouse meiosis Nucleolytic resection of DNA ends is critical for homologous recombination, but its mechanism is not fully understood, particularly in mammalian meiosis. Here we examine roles of the conserved MRN...

Borde Lab @lab_borde Jul 9, 2024

Very proud to be elected a member of this prestigious organization! Thanks to those who elected me and to my lab for their contributions😊😊

Outstanding scientists elected to EMBO Membership idw-online.de/-DMRPAA