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Lucid Scientific, Inc.

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@lucidsci

Resipher continuously measures oxygen consumption rate in standard 96-well plates, right inside your incubator. Papers, protocols and demos: lucidsci.com
Atlanta, GA lucidsci.com Joined September 2017
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Lucid Scientific, Inc. Verified account @lucidsci
What does the electron transport chain do when there is no oxygen to hand its electrons to?

Almost five years ago, one of the first Resipher publications answered that. Spinelli Chandel and Sabatini (Science, 2021) showed the SDH complex runs in reverse and uses fumarate as a terminal electron acceptor, keeping complex I and DHODH working without oxygen.

Paper: lucidsci.com/resources?publ…

#Mitochondria #Hypoxia #CellMetabolism