Check out this Research Briefing for a quick overview of our work exploring Rubisco condensation by CsLinker, an intrinsically disordered protein from Chlorella. All driven by @james_r_barrett doi.org/10.1038/s41477…
Luke Mackinder
@mackinderlab
Photosynthesis Lab using systems and synthetic biology to research the molecular basis of global carbon fixation #photosynthesis @UniOfYork #UKRIFLF
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A promiscuous algal Rubisco binding protein that binds to the large subunit, can condense plant Rubiscos and functionally complement an epyc1 mutant. Congrats @james_r_barrett + great team effort @Mihris_N,@mjplevin,@McCormick_Lab,@JNB_lab,@YorkBioimaging. doi.org/10.1038/s41477…
A blueprint of the diatom pyrenoid reveals a Rubisco encapsulating protein Shell is critical for CO2 fixation. Is it essential for global NPP? Congrats to @OnyouNam,@james_r_barrett,@ItsCarolineMck,@JNB_lab + great collab with @DemulderManon,@bengeliscious.doi.org/10.1016/j.cell…
Another major hurdle overcame in plant pyrenoid engineering to enhance CO2 fixation - how to traverse the Rubisco condensate with thylakoid membranes. Congratulations @JonikasLab @McCormick_Lab @JHennacy @NickyJAtkinson
Excited to share our latest preprint!View quoted post on X
Biogenesis, engineering and function of membranes in the CO2-fixing pyrenoid
biorxiv.org/content/10.110…
Great to be part of this multi-disciplinary project. See the insightful thread by @CharlSchaef explaining how we worked across disciplines to predict phase diagrams that we experimentally validated #pyrenoid