Pinned post Joerg J Meerpohl @meerpohl · Jan 20, 2025, Jan 20, 2025, 7:57 PM Account inactive. You can find me on Bluesky. @meerpohl.bsky.social
Joerg J Meerpohl @meerpohl · May 13, 2021, May 13, 2021, 11:32 AM How COVID broke the evidence pipeline nature.com/articles/d4158… www.nature.com How COVID broke the evidence pipeline Nature - The pandemic stress-tested the way the world produces evidence — and revealed all the flaws.
Joerg J Meerpohl @meerpohl · Apr 21, 2021, Apr 21, 2021, 8:27 AM Key concepts in clinical epidemiology: Stepped wedge trials - Journal of Clinical Epidemiology jclinepi.com/article/S0895-… www.jclinepi.com Key concepts in clinical epidemiology: Stepped wedge trials A stepped wedge trial evaluates an intervention that is implemented over a number of time periods according to a staggered timetable. Stepped wedge trials are usually cluster randomized, the interv...
Joerg J Meerpohl @meerpohl · Apr 21, 2021, Apr 21, 2021, 8:26 AM The methodological quality of individual participant data meta-analysis on intervention effects: systematic review | The BMJ bmj.com/content/373/bm… www.bmj.com The methodological quality of individual participant data meta-analysis on intervention effects:... Objective To assess the methodological quality of individual participant data (IPD) meta-analysis and to identify areas for improvement. Design Systematic review. Data sources Medline, Embase, and...
Joerg J Meerpohl @meerpohl · Apr 16, 2021, Apr 16, 2021, 8:39 AM A proposed framework to guide evidence synthesis practice for meta-analysis with zero-events studies - Journal of Clinical Epidemiology jclinepi.com/article/S0895-… www.jclinepi.com A proposed framework to guide evidence synthesis practice for meta-analysis with zero-events studies In evidence synthesis practice, researchers often face the problem of how to deal with zero-events. Inappropriately dealing with zero-events studies may lead to research waste and mislead healthcare...