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Ifigeneia Kalampouka

Verified account Terra API

@mitogenia

Ph.D.
| Health and AI Strategist @TerraAPI
| Visiting Researcher @UniWestminster
| Domain research interest: cell - light interaction & ageing
London Joined October 2021
223 Following 312 Followers 146 Posts

Latest posts 5

Ifigeneia Kalampouka Verified account @mitogenia
You inspired this, @RogerSeheult. We checked it in 33,000 clock changes from ~25,000 people: bodies don’t fully follow the clock. After clocks went forward, bedtimes ran ~12 min late and were still ~11 min late 3 weeks on. Spring clock change hits harder than autumn.
Roger Seheult, MD Verified account @RogerSeheult Oct 8
Here's just one issue associated with taking light in the morning and putting it into the evening:

ST: more morning sunlight in the eyes which advances an already delayed circadian rhythm (green arrow)

DST: more evening sunlight in the eyes which delays an already delayed circadian rhythm which causes sleepiness in the morning and insomnia at night. (red arrow)
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Ifigeneia Kalampouka Verified account @mitogenia
Thank you @RogerSeheult! Really glad the work caught your attention. And what a great opportunity to go back and reflect on next steps; spectral characterisation of the signal itself is exactly where I believe the field needs to go.
Roger Seheult, MD Verified account @RogerSeheult Apr 14
🚨🚨A recent thesis about to be published by Ifigeneia Kalampouka, PhD @mitogenia - (worth following BTW) on biophotons and cellular senescence found that isolated senescent mitochondria did two very interesting things:

1) They directly emitted measurable ultraweak photons, and
2) Mitochondria in a separate, chemically isolated chamber showed different oxygen-consumption behavior when unshielded vs shielded.

i.e. mitochondria talked to each other in different test tubes!

That does NOT prove, in a final sense, that mitochondria are “communicating with light.” - yet.

But it does show something real and intriguing: Stressed/senescent mitochondria appear to emit ultraweak light, and other physically isolated mitochondria behave differently when exposed to a non-chemical signal that is consistent with a light-based mechanism.

This is early bench science, not bedside medicine. Still, if this holds up, it could open an entirely new way of thinking about mitochondrial signaling, oxidative stress, aging, and maybe even photobiomodulation.

Really fascinating work.

There's also a whole other section where NIR is used

doi.org/10.34737/wy80y
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