Natalie Twine

@nat_twine

Team Lead and Genome Data Scientist at #CSIRO. Population-scale #Genomics platforms using #cloudcomputing #BigData #MachineLearning. Tweets are my own.

Sydney, Australia bioinformatics.csiro.au Joined June 2009

329 Following 349 Followers 414 Posts

Latest posts 5

Natalie Twine @nat_twine Oct 18, 2023

Fantastic work from our team using #ML #GWAS platform #VariantSpark and #BitEpi to identify novel disease genes and genetic interactions in Alzheimer’s disease. Read more in @SciReports nature.com/articles/s4159…
@lmfsng @MischaLundberg @ehealthresearch @TBioinf @allPowerde

www.nature.com Novel Alzheimer’s disease genes and epistasis identified using machine learning GWAS platform Scientific Reports - Novel Alzheimer’s disease genes and epistasis identified using machine learning GWAS platform

Natalie Twine @nat_twine Jul 21, 2023

@SnyderShot updates us on the new open access NIH funded resource @_hubmap - a global atlas of the human body at the cellular level @lorentz_inst

Natalie Twine @nat_twine Jul 21, 2023

Wrapping up a fantastic week learning about epistasis with a talk from @SnyderShot on the personalization of medicine and how your Fitbit can help to detect your Covid infection @lorentz_inst

Natalie Twine @nat_twine Jul 18, 2023

@lmfsng presenting at @lorentz_inst on #BitEpi for detecting epistasis in #AlzheimersDisease and #CoronaryArteryDisease. She also solves the multiple testing burden using an Empirical Bayes approach called LocalFDR @TBioinf @ehealthresearch

Natalie Twine @nat_twine Jul 17, 2023

@AmmarAlChalabi talking about Epistasis in ALS. Multiple examples using non-statistical examples. Current challenge is how to scale detection to a genome-wide approach. Working towards an answer this week at @lorentz_inst