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Very happy to share the second paper from my postdoc, published today @PLOSBiology. Here, we report that the master regulator of Salmonella virulence usurps the reign of cAMP over metabolism under infection-relevant conditions. journals.plos.org/plosbiology/ar…
journals.plos.org The master virulence regulator PhoP dictates carbon metabolism by controlling cyclic AMP synthesis... Inside macrophages, Salmonella faces magnesium scarcity that disrupts cAMP synthesis and carbon metabolism. This study shows that the PhoP regulator restores metabolic control by promoting Mg2+...