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Parker Institute

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@parkerici

Our mission is to accelerate the development of breakthrough immune therapies to turn all cancers into curable diseases.
San Francisco, CA parker.org Joined February 2016
557 Following 11K Followers 4.2K Posts

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Parker Institute Verified account @parkerici
Cancer is on the rise among younger adults, especially women, and is challenging how we think about screening, treatment, and survivorship.

In @HLTHEVENT's The Pulse, Parker Institute CEO @DrKarenKnudsen shares why this rise demands a new approach, from personalized screening and earlier detection to therapeutic cancer vaccines and better support for patients.

Thank you to @MikhailAlexa for highlighting this important conversation.

Read the full story: hlth.com/insights/artic…
hlth.com The Pulse: Cancer Is Getting Younger and More Female. What’s the Path Forward? Screening, therapeutics, and fertility are converging into a new paradigm in oncology care. In 2024, cancer was not on 32-year-old Ally Hartenstine’s mind. It wasn’t on her doctors’ either. Hartens...
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Parker Institute Verified account @parkerici
Parker Institute is heading to #SITC2026! Parker leaders, investigators, and collaborators will contribute to 32 presentations, posters, and sessions, showcasing the latest advances in cancer vaccines, cell therapies, and immunotherapy.

Congratulations to Catherine J. Wu, MD, Parker Institute Co-Director at @DanaFarber Cancer Institute, on receiving @sitcancer's 2026 Richard V. Smalley Memorial Award and Lectureship!

Explore what the Parker Institute network will be presenting: parkerici.org/news/parker-in…
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Parker Institute Verified account @parkerici
This #BreastCancerAwarenessMonth, we’re highlighting research focused on one of the biggest challenges in breast cancer: preventing metastasis.

PICI researcher @JudithAgudo1, and the team at @DanaFarber found that spreading triple-negative breast cancer cells activate the glucocorticoid receptor to evade immunity. In preclinical models, combining mifepristone with anti-PD-1 immunotherapy reduced metastatic seeding and extended survival.

Read the study in Nature: nature.com/articles/s4158…
www.nature.com A glucocorticoid–FAS axis controls immune evasion during metastatic seeding Nature - Glucocorticoid receptor activation is a key driver of resistance of triple-negative breast cancer to both CD8+ T cells and natural killer cells during initial metastatic seeding.
Parker Institute Verified account @parkerici
Personalized cancer vaccines are opening new possibilities for cancer treatment, with research exploring how they could prevent recurrence and potentially prevent cancer before it develops.

@nytimes @AgrawalNina highlights the growing momentum behind cancer vaccine research, including the work of Parker Institute researchers Dr. Robert Vonderheide at @PennCancer and Dr. Catherine Wu and Dr. Patrick Ott at @DanaFarber Cancer Institute.

Read more about the Parker researchers advancing cancer vaccine research: nytimes.com/2026/10/23/wel…
www.nytimes.com First-of-Its-Kind Vaccine Ushers in New Hope for Cancer Patients Beyond melanoma, scientists are studying cancer vaccines for glioblastoma, pancreatic cancer and more.
Parker Institute Verified account @parkerici
This #BreastCancerAwarenessMonth, we’re highlighting work from PICI researcher Robert Vonderheide, MD, PhD, and his team at @PennCancer.

The team used RAS inhibitors on precancerous lesions, nearly doubling survival vs. later treatment in mice. The team is now exploring how this “cancer interception” approach could be combined with immunotherapies, vaccines and other targeted treatments, including in models of precancerous ER+ breast cancer.

Read more: pennmedicine.org/news/new-strat…
www.pennmedicine.org New strategy intercepts pancreatic cancer by eliminating microscopic lesions before they become...