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Paul DW Kirk

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@pauldwkirk

Biostatistical machine learning. Research professor @MRC_BSU @Cambridge_Uni . All views my own.
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Paul DW Kirk Verified account @pauldwkirk
And one of our outputs as part of the In Utero programme was published today!

In our paper in Nature Medicine, we identify a placental protein that outperforms existing first-trimester biomarkers at predicting preeclampsia and fetal growth restriction, and for which there is evidence of direct involvement in the biology of failed placental invasion.

Led by Ruoyu Miao, Sungsam Gong, Ulla Sovio and Irving Aye, with Gordon Smith, Stephen Charnock-Jones and myself as joint senior authors.

cam.ac.uk/research/news/…
www.cam.ac.uk Pre-eclampsia discovery could lead to new test and treatments for at-risk pregnancies The discovery helps explain why placental cells fail to properly ‘invade’ the uterus in these two related conditions and could lead to the development of tests to help identify those at greatest risk...
Paul DW Kirk Verified account @pauldwkirk
It's been great to be a co-PI of the University of Cambridge team participating in the Wellcome Leap In Utero programme. The programme has changed my way of thinking about how I do research, and has generated some amazing results!

This video provides some background about what we have been doing and why. You'll notice that I stumble over the word "statistical" 🤦‍♂️
1:35