Pavan Bachireddy

@pbachi

Assistant Prof @MDAndersonNews. #immunotherapy single cell #genomics #leukemia. Alum @BrighamMedRes, @StanfordMed || tweets: my own

Houston, TX Joined May 2009

207 Following 459 Followers 153 Posts

Latest posts 5

Pinned post

Pavan Bachireddy @pbachi Nov 9, 2021

1/ Excited to share how T cell therapies kill #leukemia!! multi-omics + new #computational #singlecell tools for longitudinal analysis 👉unexpected answer! cell.com/cell-reports/f…

*👏* @elhamazizi! 🙏 @dpeer Cathy Wu @MDAndersonNews @CPRITTexas @ColumbiaBME @sloan_kettering

www.cell.com Mapping the evolution of T cell states during response and resistance to adoptive cellular therapy Bachireddy et al. present a computational framework for resolving cellular state dynamics from longitudinal single-cell profiles from a uniformly treated cohort of patients with relapsed leukemia....

Pavan Bachireddy @pbachi Oct 6

Thank you @MichaelDJain !! Tweetorial is pending…

Michael Jain @MichaelDJain Oct 1

This excellent manuscript from @pbachi gives some answers about why allogeneic car t sometimes fails. Two categories: 1. Pre-existing patient immune responses that attack the donor CAR T and to me surprising 2. Effectors>stem-like (different from auto!). pubmed.ncbi.nlm.nih.gov/42788887/
View quoted post on X

Pavan Bachireddy @pbachi Nov 9, 2025

Congrats to @dust_im_md for an outstanding talk from our lab! 🙏🏽 #sitc25 and @MDAndersonNews. Wonderful presentations from all #trainees at the session.

Dustin McCurry @dust_im_md Nov 9, 2025

Great to present at #SITC25 and receive a YIA! We report that genomic drivers can directly edit (ie. not transcriptional) the immunopeptidome, shaping the quantity and quality of antigens for T-cell immunotherapy. Excellent mentorship from @pbachi @ShuklaSachet @jmolldrem

View quoted post on X

Pavan Bachireddy @pbachi Oct 20, 2025

Thrilled to share our 1st preprint (!) on @biorxiv “Molecular and cellular dynamics of measurable residual disease (#MRD) progression in myelodysplastic syndromes (MDS).” Led by the indefatigable Yu-Hsiang Chen in the lab (x.com/PhRMAfoundatio…).

👉👉biorxiv.org/content/10.110…

PhRMA Foundation @PhRMAfoundation Oct 2, 2025

#PhF25 awardee Yu-Hsiang Chen, a postdoc @MDAndersonNews, is using single-cell technology to study #cancer cells that remain after stem cell transplant. Understanding these cells could help develop better treatments. @pbachi

Watch the full interview: phrmafoundation.org/news-events/bl…

View quoted post on X

Pavan Bachireddy @pbachi Dec 10, 2023

Congrats @dust_im_md on a *fantastic* #ASH2023 oral presentation - the first from the Bachireddy Lab!