Check out our recent work on second-generation bismuth peptides! Bismuth selenopeptides show exceptional kinetic stability vs Cys analogues. They effectively inhibit their targets and maintain native fold, unlocking new opportunities in medicinal chemistry & chemical biology.
Big congrats to @pritha_2107, @MinghaoShang, Kat, @Lani_D1, @UpamaliSajinika and our fantastic collaborators Toshiki and Hironobu @IPR_pr @UOsaka_en for this massive effort on second-generation bismuth peptides and proteins, just published in @angew_chem. doi.org/10.1002/anie.2…View quoted post on X
