This is a little late, but happy to share our work with @DonnaFarber3 on transcriptional control of tissue adapation and effector function in infant T cells that appeared recently in @NatImmunol. Thanks to @hipcProject and @biohub for their support. nature.com/articles/s4159…
Peter Sims
@psimslab
Professor of Systems Biology | Columbia University
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Excited to share our CITE-seq atlas of the aging human immune system across tissues. Great collaboration with @DonnaFarber3, @YosefLab, @teichlab, Jo Jones @Cambridge_Uni and partnership with @cziscience!
nature.com/articles/s4159…
nature.com/articles/s4159…
Another awesome collaboration with @DonnaFarber3! Among many other experiments, we profiled antigen-responsive T cells across the body for COVID vaccine and flu with CITE-seq. Will be interesting to see if these findings generalize to other viruses and vaccines!
We analyzed immune memory to COVID mRNA vaccines across human tissues and found durable persistence of T cell memory in lymphoid organs and lungs with enhanced regulatory functions compared to blood. @JDavisPorada collaboration with @psimslab @Teijaro_LabView quoted post on X
@columbia_MI
Awesome collaboration with @ARustgi and colleagues!
Online now: FRA1 controls acinar cell plasticity during murine KrasG12D-induced pancreatic acinar to ductal metaplasia dlvr.it/TCFFtKView quoted post on X
Fantastic work and great to see additional strong evidence of predominant 5-ALA metabolism by myeloid cells in GBM.