@rabc92_
www.science.org Evolutionarily reinforced GC-rich motif enables non-AUG translation in mammals under eIF1/5MP-med... Non-AUG translation contributes to proteome diversity, but its regulatory principles remain unclear. Here, we show that a GCC-rich upstream extension, termed the NAT1 motif, acts as a potent enhancer... 
www.cell.com Quantitative profiling of RNA modifications enriched in non-membrane-bound cellular structures... Seo et al. develop APEX-RNA-MS, a strategy integrating proximity labeling and nucleoside mass spectrometry, to characterize the spatial distribution of modified RNAs within human cells. They profile... 
www.cell.com Eukaryotic AUG initiation contexts consist of a broad range of nucleotide patterns associated with... Through a comprehensive assessment of nucleotide associations within the nucleotide contexts of AUG start codons in six eukaryotes, Tidu et al. characterize multiple nucleotide patterns centered... 
www.nature.com N4-Acetylcytidine enhances synthetic mRNA translation yield and fidelity Nature - Different RNA modifications elicit different translation elongation rates for in vitro transcribed mRNAs that result in disparate translation outputs and fidelity, as shown here for... 