@rafikelbebmd
Pinned post
www.mdpi.com Immune and Circulating Biomarkers in Hepatocellular Carcinoma: Prognostic and Predictive Relevance... Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality. Immune checkpoint inhibitor (ICI)-based combinations have become the standard first-line systemic therapy, yet objective... 🚨 Bispecific antibodies (BsAbs) in solid tumors are rapidly reshaping oncology.
Our pipeline analysis using @Larvol CLIN shows:
▫️681 trials, 183 BsAbs (📈 doubled since 2019)
▫️ Heavy focus on GI, lung, breast & GYN cancers
▫️ Dominant targets: PD1–CTLA4 (32%), PD1–VEGF, EGFR–MET
▫️ Only 38% of trials biomarker-selected
▫️ Innovation largely driven by biotech, not big pharma
@CancerMedicineJ @OncoAlert @oncodaily
🔗: onlinelibrary.wiley.com/doi/10.1002/ca…View quoted post on X
