MSKCC experience of CSF cfDNA sequencing in >700 patients now out! Actionable somatic alts in a large fraction of patients + emerging resistance alts merge with repeated sampling. Worse survival if ctDNA detected. Pre-analytic factors discussed. link.springer.com/article/10.118…
link.springer.com Real-world experience with circulating tumor DNA in cerebrospinal fluid from patients with central... Acta Neuropathologica Communications - The characterization of genetic alterations in tumor samples has become standard practice for many human cancers to achieve more precise disease... 