Robert W. Sobol

@rwsobol

Dean’s Professor of Cancer Research & Associate Director Basic Research; Legorreta Cancer Center, Brown University - studying DNA damage response in cancer

Providence, RI Joined June 2009

4.4K Following 2.6K Followers 3.7K Posts

Latest posts 5

Robert W. Sobol @rwsobol 5d

Excited to share our latest publication "Exploiting the bacterial type III secretion system of BrowZine Journal Cover Pseudomonas aeruginosa to impact genomic recombination in murine lungs" @EMGSUS @BrownUniversity @BrownUnivHealth @BrownGradSchool pubmed.ncbi.nlm.nih.gov/42992309/

pubmed.ncbi.nlm.nih.gov Exploiting the bacterial type III secretion system of Pseudomonas aeruginosa to impact genomic... The Gram-negative bacterium Pseudomonas aeruginosa encodes a Type III Secretion System (T3SS), a molecular syringe that injects bacterially-synthesized effector proteins directly into a target...

Robert W. Sobol @rwsobol Oct 31

Diesel Exhaust‐Induced miR‐133b‐3p Downregulation and CTGF‐Linked Hippo Pathway Inactivation Promote ECM Remodeling and Inflammation in Mouse Lungs - Gautam - 2026 - Environmental and Molecular Mutagenesis - onlinelibrary.wiley.com/doi/full/10.10… @EMGSUS

onlinelibrary.wiley.com Environmental and Molecular Mutagenesis | EMGS Journal | Wiley Online Library Exposure to diesel exhaust (DE) significantly contributes to air pollution. DE dysregulates miRNA expression, miRNA-target interactions promoting tissue remodeling and lung inflammation. In the...

Robert W. Sobol @rwsobol Oct 26

Assessing the Mutational Consequences of Chronic Arsenic Exposure Using Patient‐Derived Tumor Samples and In Vitro Systems - Jain - 2026 - Environmental and Molecular Mutagenesis - Wiley Online Library onlinelibrary.wiley.com/doi/full/10.10… @EMGSUS

onlinelibrary.wiley.com Environmental and Molecular Mutagenesis | EMGS Journal | Wiley Online Library Inorganic arsenic, a naturally occurring metalloid found in groundwater, is a well-established human carcinogen. Epidemiological studies from highly contaminated regions link chronic arsenic exposu...

Robert W. Sobol @rwsobol Oct 26

Gestational Low Protein Diet Increases the Susceptibility to <fi>N</fi>‐Bis(2‐Hydroxypropyl)nitrosamine‐Induced Lung Tumors in Female Wistar Rats - Ferreira - 2026 - Environmental and Molecular Mutagenesis - Wiley Online Library onlinelibrary.wiley.com/doi/full/10.10… @EMGSUS

onlinelibrary.wiley.com Environmental and Molecular Mutagenesis | EMGS Journal | Wiley Online Library This study evaluated the susceptibility to lung and kidney carcinogenesis induced by N-bis(2-hydroxypropyl)nitrosamine (DHPN) in female rats whose dams received a low-protein diet (LPD) during...

Robert W. Sobol @rwsobol Oct 16

A Hybrid Machine Learning Ensemble for Predicting Genetic Predisposition to Lung Cancer Based on Polymorphisms in the Mismatch DNA Repair Genes - Bagla - 2026 - Environmental and Molecular Mutagenesis - Wiley Online Library onlinelibrary.wiley.com/doi/full/10.10… @EMGSUS

onlinelibrary.wiley.com Environmental and Molecular Mutagenesis | EMGS Journal | Wiley Online Library The application of machine learning approaches has shown promising results in cancer prediction. In the present study, data for nine gene-based features that include MLH1 (rs1800734), MSH3 (rs26279...