Sebastiano Cultrera di Montesano

@sebacultrera

Boston, MA sebastianocultrera.com Joined February 2022

331 Following 122 Followers 87 Posts

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Sebastiano Cultrera di Montesano @sebacultrera 6d

1/11

Excited to share GENESIS, a generative model for predicting single-cell perturbation responses in unmeasured experimental conditions.

We show near-experimental-reproducibility performance, strong sample efficiency, and recovery of cancer signaling programs. 🧵

Sebastiano Cultrera di Montesano @sebacultrera Jul 3

Looking forward to presenting scDataset at #ICML2026 in Seoul next week! 🇰🇷
It's a fast, drop-in PyTorch data loader for training on single-cell datasets too large to fit in memory, giving you the speed of streaming from disk with the sampling quality of full random shuffling. 🧵

Sebastiano Cultrera di Montesano @sebacultrera May 14

Glad to have been recognised as a gold reviewer 📝🥳

ICML Conference @icmlconf May 13

Reviewers & ACs for #ICML2026 have been recognized for their service!

- Reviewers: 4439 Gold (free registration), 4437 Silver. 17749 total reviewers were assigned >= 1 paper
- ACs: 1647 receive free registration, out of 1691 who were assigned >= 1 paper

TY for your hard work!
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Sebastiano Cultrera di Montesano @sebacultrera May 8

The cross-entropy loss does not account for the structure between labels. We suggest a hierarchy-aware modification and show that it consistently improves performance in image classification across architectures, from CNNs to transformers, and across datasets 1/n

Sebastiano Cultrera di Montesano @sebacultrera Feb 17

scDataset should make the training of deep learning models on large scale single cell data fast & easy!! Check out our new release!!

Davide D'Ascenzo @davide_dascenzo Feb 17

𝘀𝗰𝗗𝗮𝘁𝗮𝘀𝗲𝘁 𝘃𝟬.𝟯.𝟬 𝗶𝘀 𝗵𝗲𝗿𝗲! 🚀

🎯 New features:
• Native DDP support (no DistributedSampler needed!)
• Built-in transforms (AnnData/HF/BioNemo)
• Auto-config module

📝 Updated paper with theoretical guarantees!

Details below 👇
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