Sid Sijbrandij

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@sytses

Co-founder & Executive Chair of GitLab. Co-founder of Kilo Code. I love economic mobility, remote work, new cities, big art, incentive design, and curing cancer

sytse.com Joined March 2009

767 Following 32K Followers 7.2K Posts

Latest posts 5

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Sid Sijbrandij @sytses Sep 18

I'm excited to share I'll be speaking at TED2027. Facing osteosarcoma changed how I see the future of medical treatments for all patients. I'll be sharing that experience on stage. Honored to be part of a line-up of future-thinking innovators. Join me in San Diego in March conferences.ted.com/ted2027/speake…

conferences.ted.com Speakers | TED2027 View the lineup of speakers for TED2027: March 1-4 | San Diego, California

Sid Sijbrandij @sytses Oct 19

We’ve just made public 125,091 DICOM radiology images from across my cancer journey (link below). The data is both longitudinal and multi-modal, dated and linked to my treatment timeline, so you can compare imaging across initial diagnosis, standard of care, first remission, “founder mode cancer care”, and second remission. It’s viewable in OHIF, the standard open-source viewer used in radiology research.

Given the long history of applying deep learning to radiology, we’re hoping to see a variety of methods and models applied to my data. If you find something interesting, please reach out to cancer@sytse.com, or if you know a researcher who should see this, tag them below.

Thanks to Terra LaFerriere for organizing these images, and Kamil Slowikowski for building osteosarc.com into the resource it is.

Sid Sijbrandij @sytses Oct 15

Nabiha has assembled a smart team that lowered the price of cell preservation. Certainly worth considering before you go in for cancer chemotherapy.

Dr. Nabiha Saklayen Verified account @nabihasaklayen Oct 15

In partnership with Vinod Khosla (@vkhosla), I’m proud to introduce Reservoir.

Billionaires have owned their cells for years. Starting today, you can too.

Sign up today: withreservoir.com

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Sid Sijbrandij @sytses Oct 6

It was great discussing my cancer journey with Mike and Devan. They have deep bio and AI knowledge and it showed in the conversation.

632nm Verified account @632nmPodcast Oct 6

What if the best way to fight cancer is to think like a founder?

This week we spoke with Sid Sijbrandij (@sytses), co-founder of @gitlab, about his experience developing experimental treatments for his own cancer.

When standard-of-care treatments could no longer control his cancer, Sid went “founder mode,” assembling a team of researchers to attack the disease with a combination of experimental treatments never before used together.

Taking a lesson from his success building GitLab, he’s made his medical data open-source for researchers to continue to innovate.

We discuss the science of Sid’s cancer journey and the challenge of making highly personalized cancer treatments faster, cheaper, and accessible to more patients as sequencing costs fall and AI accelerates biological discovery.

Full episode here on X and YouTube (see comment).

@MikeDubrovsky @dshahh

Timestamps:
00:00 - Intro
01:10 - mRNA Vaccine Basics
10:20 - Costs of mRNA Vaccine Development
15:59 - Lessons from Building GitLab
19:19 - Standard of Care for Cancer
24:50 - Sid’s Life Story and GitLab
30:49 - Going Founder Mode Against Cancer
42:03 - Selecting Experimental Treatments
50:38 - How Did Sid Know Treatments Were Working?
58:08 - AI for Treatment Assistance
1:02:54 - Making Personalized Treatments Affordable
1:08:17 - Where are the Levers for Improving Drug Development?
1:10:54 - Most Promising Areas of Drug Development
1:17:14 - The Happy Accident of Sid’s Biotech Investments
1:21:07 - Reflecting on Building GitLab
1:22:46 - How Does Sid Start So Many Companies?
1:26:02 - Finding the Right People for Early Companies
1:34:19 - Will the Bahamas be the Next Singapore?
1:38:42 - Advice for Young Scientists

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Sid Sijbrandij @sytses Sep 11

Omanta omanta.com was part of the latest YC batch and is working to help patients with complex cancer cases. The CEO, Alfredo Gonzalez, was a bioinformatician on my team and did an amazing job. While I’m not involved with this particular company, I wish Alfredo all the best and hope they’ll be very successful. It’s great to see more options becoming available for cancer patients.