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Simon Hill MSc, BSc

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@theproof

Nutrition scientist & physio. Host of The Proof (50M+ listens). Author, The Proof is in the Plants. The evidence on living longer – minus the dogma.
Australia nutritionscientist.substack.com Joined October 2019
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Simon Hill MSc, BSc Verified account @theproof
Interesting study.

A study that compared low-carb (30% calories) plant-rich diet versus a healthy Nordic diet (50-55% calories from carbs) vs usual care in patients with pre-diabetes and TD2.

Outcomes of interest: Liver fat, body weight and other cardio-metabolic risk factors.

Ad lib study, and patients bought and prepared their own food so we get good generalisability. Important to underscore it wasn't a calorie restriction weight-loss study.

Diet surveys and blood biomarker data to verify dietary intake.

Length: 12 months

Liver fat reduced comparably on the low-carb and nordic diets (about a fifth of liver fat was lost in both dietS)

Nordic diet did significantly better than the usual care diet for a host of other outcomes and better than the low carb diet for glycemic control.

Authors concluded:

"Thus, the healthy nordic diet was overall the most effective diet for the treatment of T2D and prediabetes, including improving multiple metabolic disorder seen in NAFLD."

"Notably, our descriptive analysis showed that more than half (~ 54%) of the randomized patients to the healthy nordic diet had a remission of NAFLD, compared with only ~17% after the other two diets, and the
healthy nordic diet group also had the highest rate of remission of prediabetes"

Note: Not directly comparable to the more recent Sam Klein/Max Peterson trial as that was energy restricted, food provided and a ketogenic diet. The low carb diet in this intervention was higher carb (relatively), focussed on plant fats and ad-lib.

Cc @ApoDudz @reallyoptimized @mpetersenmdphd

nature.com/articles/s4146…
www.nature.com Effects of an anti-lipogenic low-carbohydrate high polyunsaturated fat diet or a healthy Nordic... Nature Communications - Previous short-term clinical trials suggested plant-derived polyunsaturated fatty acids (PUFA) reduced liver fat. Here the authors report in a controlled randomised clinical...
4 replies 2 reposts 21 likes 2.7K views View on X
Simon Hill MSc, BSc Verified account @theproof
A new review of 87 trials found the whole grain sweet spot: 60–100 g a day, roughly 4–6 servings. Benefits started at 30–40 g.

LDL, triglycerides, blood pressure, blood sugar, and waist all moved in the right direction.

Full breakdown below.
9 replies 6 reposts 54 likes 8.8K views View on X