Van de Plas Lab

We are the @RafVandePlas research lab at the Delft Center for Systems and Control @tudelft. We develop signal processing algorithms & machine learning methods for multimodal molecular imaging & mass spectrometry, exploring human tissue in health & disease vandeplaslab.tudelft.nl

Come check out the work from Van de Plas lab members and our collaborators throughout the week at #ASMS2026 — posters, oral sessions, and a workshop panel. Overview below.

Since last ASMS — our Analytical Chemistry paper applying Stable Principal Component Pursuit (SPCP) to IMS. Going beyond PCA by capturing dense noise and sparse variation.

Led by Dr. Roger Moens (my group), who recently defended his PhD.

doi.org/10.1021/acs.an…

#ASMS2026

Since last #ASMS — check our IEEE TSP paper: the Spiked Mixture Model. Signal-processing theory unlocking low-SNR signal recovery, incl. for IMS.

Led by Paul-Louis Delacour (PhD candidate, my group) with Sander Wahls (KIT) & Jeff Spraggins (Vanderbilt).

doi.org/10.1109/TSP.20…

Some of our work since last ASMS — check out our Sci Adv paper: a spatiomolecular lipid atlas of human kidney from 29 donors

Co-led by Léonore Tideman (Van de Plas lab) with Melissa Farrow & Elizabeth Neumann (Spraggins lab). Part of @_hubmap.

doi.org/10.1126/sciadv…

#ASMS2026