The Veesler Lab

@veeslerlab

Pathogen entry into cells, host immune responses & vaccine design: structural biology, protein design, virology & immunology @HHMINEWS @UWBiochemistry

Seattle, WA veeslerlab.com Joined October 2014

872 Following 6.2K Followers 1.3K Posts

Latest posts 5

The Veesler Lab @veeslerlab Apr 29

Can we use #proteindesign to develop countermeasures before viruses cause pandemics?

We computationally designed an ultrapotent and broadly neutralizing deltacoronavirus miniprotein.
Led by Nathan Avery
@hhmi_science

1/12

pnas.org/doi/10.1073/pn…

www.pnas.org Computational design of an ultrapotent deltacoronavirus miniprotein inhibitor | PNAS Multiple spillovers of porcine deltacoronavirus (PDCoV) into humans in Haiti highlight its zoonotic potential and the need for targeted interventio...

The Veesler Lab @veeslerlab Apr 28

How are host proteases promoting coronavirus entry into cells? Find out by reading our latest manuscript led by Matt McCallum Brett Case Jack Brown @YoungjunPark11 in collaboration with @msdiamondlab

1/19

The Veesler Lab @veeslerlab Feb 3

First vaccine targeting SARS virus family enters human trials ipd.uw.edu/2026/02/gbp511… via @UWproteindesign

www.ipd.uw.edu First vaccine targeting SARS virus family enters human trials – Institute for Protein Design The computer-designed vaccine aims to protect against coronaviruses that haven't yet emerged, including pandemic threats

The Veesler Lab @veeslerlab Nov 12, 2025

Delighted to share the peer-reviewed version of our article describing a prefusion-stabilized MARV GP vaccine immunogen and a best-in-class MARV neutralizing and protective antibody!

Led by Amin Addetia with @VirBiotech

@HHMINEWS

nature.com/articles/s4158…

www.nature.com Potent neutralization of Marburg virus by a vaccine-elicited antibody Nature - A newly developed monoclonal antibody, MARV16, broadly neutralizes all Marburg virus isolates and provides effective protection in guinea pigs with Marburg virus disease.

The Veesler Lab @veeslerlab Nov 1, 2024

Excited to share our latest work elucidating the mechanisms of coronavirus entry into cells!

Led by @Dr_MattMcCallum on our side in collaboration with Huan Yan's lab (TaiKang Center for Life and Medical Sciences)

nature.com/articles/s4158…

1/5

www.nature.com Design of customized coronavirus receptors Nature - A strategy using engineered functional customized viral receptors enables the development of functional infection models for coronaviruses whose native cellular receptors are unknown.