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What is possible when participants power research
In a new collaborative study publish in @ScienceMagazine today, researchers at 23andMe and @DanaFarber used data from more than 3.3 million 23andMe consenting research participants to characterize a rare inherited EGFR variant that significantly elevates lung cancer risk, while also exploring its relationship to smoking, polygenic risk, ancestry and geography.View quoted post on X
We found that the EGFR T790M genetic variant is carried by about 1 in 15,000 people in the United States, and is associated with a 25-fold increased risk of lung cancer. Among people who never smoked, carriers had a 60 fold higher odds of developing lung cancer than non-carriers.
Illustration credit: @oliveruberti
Learn more about the study and work here: 23andme.org/blog/articles/…