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Frank Xie lab

@549nm

Lighting up genome regulation in human development and disease. Views are my own.
Asst. Prof. @ Cleveland Clinic frankxielab.com Joined June 2017
273 Following 304 Followers 242 Posts

Latest posts 5

Frank Xie lab @549nm
I knew we could make it and it does. Congratulations to the team!
Anastasios Pavlopoulos @TassosAP Apr 4, 2023
THANK YOU @HFSP!!! It’s official and it’s a dream come true to receive an #HFSPResearchGrants with Frank Xie @549nm and Léo Guignard @GuignardLab to study the developmental regulation of bilateral symmetry. Stay tuned for job ads soon. #ParhyaleRocks
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Frank Xie lab @549nm
We previously developed single-cell imaging methods to probe the accessible genome organization and mechanism. In this follow-up preprint, my colleagues provide novel new insight on how the 3D accessible genome shapes gene co-expression in single cells.
biorxiv.org/content/10.110…
www.biorxiv.org Spatial organization of the 3D genome encodes gene co-expression programs in single cells Deconstructing the mechanism by which the 3D genome encodes genetic information to generate diverse cell types during animal development is a major challenge in biology. The contrast between the...
Frank Xie lab @549nm
Very impressive graphic summary to our work from Steven Wang's lab at Yale.
Siyuan (Steven) Wang @SStevenWang Jul 7, 2022
Check out our new spotlight article in Trends in Genetics highlighting a recent work from Drs. Bin Zhang @binzmit, Robert Tjian @TjianDarzacq, and Zhe Liu @zhejliu's teams. We thank @TrendsGenetics for the article invitation! And congrats to @ChengYubao! authors.elsevier.com/sd/article/S01…
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