Anna Greka

@AnnaGreka

MD PhD Professor @HarvardMed @BrighamWomens @broadinstitute | membrane proteins and disrupted homeostasis in kidney, metabolic, degenerative genetic diseases

Massachusetts, USA grekalab.org Joined October 2015

953 Following 2.5K Followers 1.1K Posts

Latest posts 5

Anna Greka @AnnaGreka Jul 3, 2025

Delighted to share our latest, expertly led by @KatlynGabriel_ and @ChoahK:

FAF2 is a bifunctional regulator of peroxisomal homeostasis and saturated lipid responses

Impactful work with therapeutic potential by our @GrekaLab team at @broadinstitute!

science.org/doi/10.1126/sc…

www.science.org FAF2 is a bifunctional regulator of peroxisomal homeostasis and saturated lipid responses Genome-wide CRISPR screen reveals FAF2 as a general bifunctional regulator of peroxisomes and cellular responses to lipotoxicity.

Anna Greka @AnnaGreka Mar 10, 2025

Thank you @EricTopol for this vital conversation about untapped opportunities in this pivotal moment for biomedicine.

Eric Topol Verified account @EricTopol Mar 9, 2025

Research support for rare diseases, which cumulatively affect ~30 million Americans, is primarily derived from NIH.
Such work is exemplified by @AnnaGreka @broadinstitute in a new Ground Truths podcast.
Open-access, w/ transcript, full video, no ads

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Anna Greka @AnnaGreka Sep 20, 2024

Delighted to share our latest @GrekaLab story in collaboration with @WuLabHarvard on the molecular basis of TMED9 cargo receptor oligomerization and entrapment of misfolded cargo in the early secretory pathway. @broadinstitute @harvardmed @MassGenBrigham
science.org/doi/10.1126/sc…

www.science.org Molecular basis of TMED9 oligomerization and entrapment of misfolded protein cargo in the early... Cryo-EM structures reveal TMED9 oligomerization and interaction with misfolded proteins to exert cytotoxicity and disease.

Anna Greka @AnnaGreka May 23, 2024

Our latest out today in @CellReports

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Congratulations to @ayshwaryas Yiming Zhou, Katherine Vernon, a great group of co-authors @Zimmermk1986 @ClatworthyLab Aviv Regev and many other amazing collaborators. Grateful to @humancellatlas and @cziscience for their support!

Cell Reports @CellReports May 22, 2024

Protective role for kidney TREM2high macrophages in obesity- and diabetes-induced kidney injury dlvr.it/T7FFMb
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Anna Greka @AnnaGreka Mar 1, 2024

#RareDiseaseDay2024
@GrekaLab @harvardmed @BrighamResearch
Thank you @TEDTalks for the opportunity to share this idea with the world!
👇👇👇

Brigham and Women’s Research @BrighamResearch Oct 4, 2023

"The amazing thing about science is that if you follow your curiosity, it can lead you to untold scientific treasures" - @AnnaGreka

Watch Dr. Greka's TED Talk to learn more about her work and the impact it can have on millions of people globally.

ted.com/talks/anna_gre…
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