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Benedetta Bolognesi

@Bennibolo

Biologist, Explorer. Group Leader @IBECBarcelona. Protein Phase Transitions.
Barcelona, Spain Joined December 2011
1.3K Following 1.1K Followers 1.1K Posts

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Benedetta Bolognesi @Bennibolo
Our latest paper is out! We built a large-scale mutational map of amylin to understand how sequence drives #amyloid formation, a process linked to type 2 #diabetes🩸📈📉. It’s a step towards connecting molecular mechanisms with human genetic variation in a systematic way.
IBEC @IBECBarcelona Mar 30
🔬 Investigadores de l'#IBEC creen un mapa mutacional de l’amilina que mostra com certes mutacions poden accelerar o frenar la formació d’agregats tòxics vinculats a la diabetis tipus 2. 

📖 ibecbarcelona.eu/an-unprecedent…
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Benedetta Bolognesi @Bennibolo
New cocktail 🍹 in town - in collaboration with @BenLehner : Massive combinatorial mutagenesis + amyloid kinetics selection + thermodynamic modelling showing us the portrait 🎨 of an amyloid transition state. Read about it in this great thread by co-first author @immunobananna
Alzheimer’s disease 🧠starts with a molecular domino effect - but what triggers the first piece to fall?
In our new study we cracked open the black box of early protein aggregation, and the findings could reshape how we fight neurodegeneration. 🧵👇

science.org/doi/10.1126/sc…
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Benedetta Bolognesi @Bennibolo
Very grateful to @FundacionLuzon & @CaixaResearch @FundlaCaixa for their support in this journey which I hope will bring my lab @IBECBarcelona , @LukeMcAlary & Bryony Thompson to make important contributions towards a systematic understanding of #ALS #ELA #MND
🔬 Ayer estuvimos en @CaixaForum Madrid entregando nuestra beca #TalentoELA al proyecto ganador de este año para investigar sobre la ELA.

🤝 Este proyecto de investigación será financiado durante tres años por @FundlaCaixa y por nuestra fundación.

👏🏼 ¡ENHORABUENA!
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