Casper Goverde (@CasperGoverde)

Casper Goverde @CasperGoverde Jun 20, 2024

The last two years of my PhD I've worked with great pleasure with @MartinPacesa @GoldbachNico @befcorreia and many others. When we started this journey we had no idea where this project would lead us, so I feel deeply humbled that we managed to publish our work in Nature.

Martin Pacesa @MartinPacesa Jun 19, 2024

Today in @Nature we present the results of our exploration of the soluble protein universe and the design of functional soluble membrane proteins with @CasperGoverde @GoldbachNico @befcorreia 1/6

nature.com/articles/s4158…

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Casper Goverde @CasperGoverde Apr 3, 2024

After three years of my PhD in the field of protein design, I got the opportunity to share my view on it thanks to this amazing collaboration with Dina Listov and Sarel Fleishman from @WeizmannScience Here is a tweetorial! Full review is available here: doi.org/10.1038/s41580…

Casper Goverde @CasperGoverde Feb 6, 2024

Incredible work by the Levy lab! Using AlphaFold2 to generate a database of the multimeric proteome. This collaboration easily ranks among my top favorites 😍 Happy to share our joint effort with the world 🌟

elevyLab @ElevyLab Feb 6, 2024

So happy to see our work published at @CellCellPress !

We added the quaternary structure dimension to proteome-wide, #AlphaFold2 predictions:

The published paper: sciencedirect.com/science/articl…

The original 🧵 (Two more experimental structures since!)
x.com/ElevyLab/statu…
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Casper Goverde @CasperGoverde May 10, 2023

Is it possible to design soluble analogs of integral membrane proteins using deep learning? The answer is yes! In our latest study we've successfully created novel soluble proteins with claudin, rhomboid protease, and GPCR-like topologies. Read more here biorxiv.org/content/10.110…

www.biorxiv.org Computational design of soluble analogues of integral membrane protein structures D e novo design of protein folds with complex topologies and intricate structural features using solely computational means remains a significant challenge. Here, we use a robust deep learning...

Casper Goverde @CasperGoverde Feb 13, 2023

Excited to be a visiting grad student in the Ovchinnikov lab at Harvard University! First day filled with great energy and a positive atmosphere. Can’t wait to collaborate and learn over the next few months! @sokrypton

Casper Goverde

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