Elif Nur Firat-Karalar

@CytoLabKoc

scientist studying centrosomes, cilia and centriolar satellites; associate prof @kocuniversity; alumna @ucberkeley @stanford; mom of 3👦1👧; 2X ERC StG

İstanbul, Türkiye cytolab.ku.edu.tr Joined November 2015

805 Following 6.4K Followers 2.7K Posts

Latest posts 5

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Elif Nur Firat-Karalar @CytoLabKoc Jul 9, 2024

Over the moon to share that I’ve been elected as an @EMBO member! This wouldn't have been possible without my fantastic mentors and collaborators, passionate past and present team members @kocuniversity, funding from @EMBO_YIP, @ERC_Research, @Tubitak and support of my family.

EMBO @EMBO Jul 9, 2024

Outstanding scientists elected to EMBO Membership: in EMBO’s 60th anniversary year, 100 new members and 20 associate members join the community

embo.org/press-releases…
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Elif Nur Firat-Karalar @CytoLabKoc Oct 10

Excited to share our new preprint on SatelliteQ! We developed an open-source Fiji–Python workflow to make quantifying centriolar satellites in microscopy images easier, more reproducible, and more accessible. We are excited to see how others will use it!
biorxiv.org/content/10.648…

www.biorxiv.org SatelliteQ: an open-source workflow for multidimensional, object-based quantification of centriolar... Centriolar satellites are membrane-less organelles that store, modify and traffic proteins, in particular those of the centrosome and the primary cilium, and their deregulation is linked to ciliopa...

Elif Nur Firat-Karalar @CytoLabKoc Jun 16

Excited to share our new @JCellBiol paper! We show that centriolar satellites assemble via a hierarchical pathway driven by PCM1 multimerization , revealing how these membrane-less organelles assemble and function. Huge thanks to our amazing team, collaborators & @ERC_Research.

Journal of Cell Biology @JCellBiol Jun 11

.@CytoLabKoc show PCM1 multimerization scaffolds centriolar satellite assembly & drives stepwise client recruitment. Disrupting this homeostasis impairs ciliary signaling & #mitosis. Key insights into how this membraneless organelle forms & remodels hubs.la/Q04l3fVz0

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Elif Nur Firat-Karalar @CytoLabKoc May 22

How do migrating cells coordinate actin, microtubules, and focal adhesions? Our preprint identifies CCDC66 as an actin–microtubule crosslinker that promotes microtubule targeting to FAs and maintains balance between protrusion and contractility.

biorxiv.org/content/10.648…

Elif Nur Firat-Karalar @CytoLabKoc Apr 28

Huge congratulations to @ghotamis on being elected to the National Academy of Sciences. A remarkable and truly deserved honor!

Gunes Parlakgul Verified account @gparlakgul Apr 28

So proud of my mentor Gokhan Hotamisligil @ghotamis for his election to the National Academy of Sciences. So well deserved!!
nasonline.org/news/2026-nas-…
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