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Dominik Lindenhofer

@DLindenhofer

Heidelberg, Germany Joined March 2020
95 Following 88 Followers 8 Posts

Latest posts 2

Dominik Lindenhofer @DLindenhofer
We are excited to share that our paper on SDR-seq, a combined single-cell DNA-RNA sequencing method, has been accepted and published in @naturemethods! 🎉
Watch co-author Julia Bauman’s video on how SDR-seq links coding & non-coding variants to gene expression.
Julia Bauman Verified account @JuliaBauman2 Sep 1, 2025
What good is a science communication channel if you don't get to talk about your own papers on it occasionally, right?😊

We developed a method to simultaneously sequence single-cell DNA and RNA targets, enabling association of genomic variants (including non-coding!) with gene expression changes.

Out today in @naturemethods, from @LarsMSteinmetz lab led by @DLindenhofer! Link below⬇️
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Dominik Lindenhofer @DLindenhofer
Very pleased to share our recent preprint for a targeted scDNA-scRNA-seq method. Thx a lot to everyone who contributed!

biorxiv.org/content/10.110…
www.biorxiv.org Functional phenotyping of genomic variants using multiomic scDNA-scRNA-seq Genomic variation ranging from single nucleotide polymorphisms to structural variants can impact gene function and expression, contributing to disease mechanisms such as cancer progression. The...
Lars Steinmetz @LarsMSteinmetz Jun 5, 2024
We are very happy to share our preprint (D. Lindenhofer et al.) of a high-throughput targeted scDNA-scRNA-seq (SDR-seq) method. Impactful for any application with a need to associate coding and non-coding variants to gene expression in tissue samples and cell culture systems.
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