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Lars Steinmetz

@LarsMSteinmetz

Chair Genetics Dept @StanfordMed, Co-Director @StanfordGenome, Director @LiSciAlliance & Lab head @EMBL. Cofounder @SOPHiAGENETICS @RecombiaBio @levitasbio
Palo Alto, CA embl.org/groups/steinme… Joined November 2015
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Lars Steinmetz @LarsMSteinmetz
We are excited to share that our paper (D. Lindenhofer et al.) on SDR-seq, a combined single-cell DNA-RNA sequencing method, has been published in @naturemethods! 🎉 
Watch co-author Julia Bauman’s video on how SDR-seq links coding & non-coding variants to gene expression.
Julia Bauman Verified account @JuliaBauman2 Sep 1, 2025
What good is a science communication channel if you don't get to talk about your own papers on it occasionally, right?😊

We developed a method to simultaneously sequence single-cell DNA and RNA targets, enabling association of genomic variants (including non-coding!) with gene expression changes.

Out today in @naturemethods, from @LarsMSteinmetz lab led by @DLindenhofer! Link below⬇️
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Lars Steinmetz @LarsMSteinmetz
We are very happy to share our preprint (D. Lindenhofer et al.) of a high-throughput targeted scDNA-scRNA-seq (SDR-seq) method. Impactful for any application with a need to associate coding and non-coding variants to gene expression in tissue samples and cell culture systems.