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Goldrath Lab

@GoldrathLab

UCSD Biological Sciences. Transcriptional regulation of T cell memory. #goldrathgophers
La Jolla, San Diego goldrathlab.com Joined December 2017
139 Following 2.6K Followers 324 Posts

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Goldrath Lab @GoldrathLab
CD8 T cell memory differentiation is controlled by the druggable target BRD4. @JJMilnerLab (just started his own lab at UNC!) and Clara Toma (off to @UW MSTP program) show that terminal effector cells are regulated by BRD4 binding of super enhancers.
x.com/JExpMed/status…
.@JJMilnerLab, @GoldrathLab and colleagues reveal the #chromatin reader BRD4 controls the differentiation and maintenance of a terminally differentiated CD8 T cell state. bit.ly/2Svt3AC
#InfectiousDisease #HostDefense #TumorImmunology
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