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Tobias Nørby Hansen

@HanseNrby

PhD student @ChristianAOlsen lab at @UCPH_health | Development of novel inhibitors of Sirtuins | Chemical Biology | Scout and leader with @FDFerne
Rødovre, Danmark Joined April 2014
705 Following 139 Followers 86 Posts

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Tobias Nørby Hansen @HanseNrby
The final version of our work is out now in @JACS_Au - it's open acess so give it a read to see how we discovered a simple substitution pattern to selectively inhibit HDAC6 and 11 with small molecules 🧪

pubs.acs.org/doi/full/10.10…
pubs.acs.org Sulfur(VI) Fluoride Exchange Chemistry in Solid-Phase Synthesis of Compound Arrays: Discovery of... Abstract. Multistep synthesis performed on solid support is a powerful means to generate small-molecule libraries for the discovery of chemical probes to d
Ever wondered why sulfate diesters are not found in medicinal chemistry? We did - therefore we introduced #SuFEx on resin in a 'click and cleave' approach 🧩 Using #HDAC as a test case we found multipel selective inhibitors 🧪
Check out on @ChemRxiv
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Tobias Nørby Hansen @HanseNrby
Ever wondered why sulfate diesters are not found in medicinal chemistry? We did - therefore we introduced #SuFEx on resin in a 'click and cleave' approach 🧩 Using #HDAC as a test case we found multipel selective inhibitors 🧪
Check out on @ChemRxiv
We have a new preprint out on #SuFEx chemistry used in the solid-phase synthesis of small molecules, to deliver a number of new #HDAC inhibitors.
@UCPH_health @UCPH_CBP

chemrxiv.org/engage/chemrxi…
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Tobias Nørby Hansen @HanseNrby
Come and work with us for an exciting project on ⚡️-chemistry to overcome challenges in modifying peptides and proteins.
We have a PhD position available for an exciting project in the lab @UCPH_health, @UCPH_CBP . We will develop new organic synthetic methods for modification of peptide/protein drug candidates.

Deadline for applications 19 January
For more information 👇

candidate.hr-manager.net/ApplicationIni…
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