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IMSB_ETH

@IMSB_ETH

Institute of Molecular Systems Biology at @ETH_en @ETH_DBIOL - Contributors: Members of IMSB
ETH Zurich imsb.ethz.ch Joined January 2012
123 Following 844 Followers 317 Posts

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IMSB_ETH @IMSB_ETH
Congratulations to the @Picotti_Lab, and lead authors @CathyMarulli and Christian Dörig, for their exciting new paper in @NatureBiotech 🥂
Picotti Lab @Picotti_Lab Oct 16, 2024
Our paper describing a new method (FLiP-MS) for the global profiling of protein complex dynamics is out @NatureBiotech !

Read here👉: doi.org/10.1038/s41587…

🔬 Highlights:

- Uses an experimental library of peptide markers integrated with a structural proteomics workflow.

- Probes the assembly state of hundreds of protein complexes simultaneously across conditions directly from whole cell extracts, informing on binding interface occupancy.

- Supports the structural modelling of protein complexes and the design of compounds targeting them

Congratulations to shared first authors @CathyMarulli and Christian Dörig and thanks to our collaborators @LabBarral and @TorstenSchwede lab

@ETH_en #Proteomics #PPIs #SystemsBiology #LiPMS #teammspec #DrugDiscovery
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