Jason Butler

@JMBstemcell

Living the dream!

Joined August 2012

351 Following 257 Followers 162 Posts

Latest posts 5

Jason Butler @JMBstemcell Jan 3, 2025

Excited to share our latest work published today in @SciImmunology and featured on the cover! This study demonstrates that thrombospondin-1 (Thbs1) is a driver of hematopoietic aging and that targeting Thbs1 suppresses inflammaging and restores systemic and HSC healthspan.

Science Immunology @SciImmunology Jan 3, 2025

Science #Immunology's January issue is out!

This month's cover depicts how deleting #thrombospondin1 can reverse aging-associated defects known as #inflammaging in hematopoietic stem cells in mice.

Read this research and more: scim.ag/3BI2A9Z

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Jason Butler @JMBstemcell Apr 11, 2023

Very excited to share our recent publication showing that restoring BM niche function rejuvenates aged HSCs @NatureComms (rdcu.be/c9EAP)! Congrats to @pradeepvpr, @GusThePolice, @mc_gutty, and the rest of the talented crew!

Jason Butler @JMBstemcell Aug 3, 2022

Excited to announce the lab has moved to @UFMedicine @ufhealthcancer. Equally excited for my new role as Vice Chief of Research in Hem/Onc. Many thanks to @DrMarkham & @jdlicht for this wonderful opportunity. Looking forward to working with this amazing scientific community!

Jason Butler @JMBstemcell Apr 14, 2020

Hope everyone is staying safe and healthy. Check out our newest paper in @JExpMed. Turns out HSCs don't like it when you mess with mTOR signaling in endothelial cells. Thanks to the whole lab and Pradeep Ramalingam @pradeepvpr! #HSCaging rupress.org/jem/article/21…

Jason Butler @JMBstemcell Feb 3, 2020

Excited to share our new study showing that endothelial MAPK impairs HSC function via chronic inflammation and that HSC defects can be reversed by targeting the niche published in @NatureComms. Congrats to @pradeepvpr and the rest of the talented crew! rdcu.be/b08fK