Jay Brito Querido

@Jayquerido

Assistant Professor at the @UMichMedSchool and Research Assistant Professor at the @UMLifeSciences

Ann Arbor, MI lsi.umich.edu/science/our-la… Joined June 2009

741 Following 881 Followers 655 Posts

Latest posts 5

Pinned post

Jay Brito Querido @Jayquerido Sep 19, 2024

We've just celebrated the 2nd anniversary of my lab at @UMichMedSchool, @UMLifeSciences and @umichrna. I couldn't have asked for a better gift – my first @NIH R01 Grant was awarded on my very first attempt! A total of $3.1 million to study #mRNA #translation in #neurodegeneration

Jay Brito Querido @Jayquerido Oct 7, 2024

I look forward to hosting @mitchguttman from @Caltech for a seminar at the @UMLifeSciences. #RNA @umichrna

Jay Brito Querido @Jayquerido Aug 8, 2024

Our new paper is finally out!
We discovered that the human tumor suppressor protein Pdcd4 binds to the #mRNA entry channel in the 40S ribosomal subunit, where it blocks the eIF4F-independent role of eIF4A. #ribosome #CryoEM @umichrna @UMLifeSciences
nature.com/articles/s4146…

Jay Brito Querido @Jayquerido May 23, 2024

Congratulations, Fengrong (@VernCarruthers Lab), on this excellent paper about mRNA translation initiation and Toxoplasma stage conversion. I'm glad my lab was able to contribute. Great things are yet to come!
nature.com/articles/s4146…

#Science #ribosome #mRNA #Parasitology

www.nature.com Translation initiation factor eIF1.2 promotes Toxoplasma stage conversion by regulating levels of... Nature Communications - Wang et al. show that Toxoplasma gondii translation initiation factor eIF1.2 is critical for acute to chronic stage transition during infection, underscoring the importance...

Jay Brito Querido @Jayquerido May 3, 2024

I am excited to share our new preprint. Human tumor suppressor protein Pdcd4 binds at the mRNA entry site in the 40S, where it blocks the eIF4F-independent role of eIF4A during recruitment and scanning.
biorxiv.org/content/10.110…
#CryoEM #science #mRNA #ribosome

0:22